Systemic Sclerosis - An Update
نویسندگان
چکیده
منابع مشابه
Systemic sclerosis: an update.
Systemic sclerosis (SSc) is a complex and heterogeneous chronic illness characterized by substantial patient to patient variability in clinical manifestations, internal organ involvement, and outcome. Genetic factors contribute to disease susceptibility, but environmental influences also play a significant role. The pathogenesis of SSc encompasses vascular, immunological, and fibrotic processes...
متن کاملSystemic Sclerosis - An Update
Systemic sclerosis (SSc) is a clinically heterogeneous, systemic disorder affecting connective tissue of skin, internal organs, and walls of blood vessels. It is characterized by alterations of the microvasculature in the form of hypoxia, digital ulcers, and pulmonary arterial hypertension; disturbances of the immune system, including dysbalance of cytokine expression, autoantibodies (Auto-ab),...
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Systemic sclerosis affects multiple internal organs and systems and is characterized by high clinical variability. Early diagnosis of the disease itself and of organ involvement plays a key role in the management of systemic sclerosis. The prognosis for each patient is equally important. In recent years there has been significant progress in our understanding of the pathogenesis and clinical co...
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Systemic sclerosis (SSc) is an autoimmune disease characterized by vasculopathy, immune cell activation, and fibrosis of the skin and internal organs. Over the past few years, a role for genetics in the susceptibility for SSc has been established. This review aims to provide an update on the progress made in the past year or so within the field of SSc genetics research. This year has been of pa...
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Pulmonary arterial hypertension (PAH) affects 10% to 15% of patients with systemic sclerosis and is a major cause for disease-related morbidity and mortality. Over the past decade, significant progress has been made in the understanding of the pathophysiologic mechanisms underlying PAH. This progress led to the development of several new treatment options and, as a result, dramatically improved...
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ژورنال
عنوان ژورنال: Laboratory Medicine
سال: 2011
ISSN: 0007-5027,1943-7730
DOI: 10.1309/lm9ob5bz4osnvgvf